Bladder pain is caused by a chronic inflammation of the urinary bladder. This inflammation is associated with a relative thermal hyperalgesia referred to the hind limb. Palmitoylethanolamide (Normast) attenuates this referred hyperalgesia in a dose-depended fashion. These result implicates that Palmitoylethanolamide (Normast) can be seen as a novel treatment for bladder pain.
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